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The immediate activation of the adaptive ER stress response was reduced, but not blocked by GSTP1

Finally, several copper complexes have strong anticancer activities by inhibiting the UPS in vitro and in vivo (Table 1)

Xu X, Wang G, Ai L et al (2018) Melatonin suppresses TLR9-triggered proinflammatory cytokine production in macrophages by inhibiting ERK1/2 and AKT activation