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Sleep Architecture and Delta-Wave Promotion: In rabbit, rat, cat, and limited human EEG studies, intravenous or intracerebroventricular DSIP administration significantly increased total sleep time, prolonged slow-wave sleep (SWS) duration, increased delta-wave power, and reduced sleep latency without altering REM sleep proportion

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HDAC6 inhibitor Ricoliostat: HDAC6 inhibitors can promote the degradation of protein aggregates or protect neurons from oxidative stress, hence can be used as possible drugs for treating peripheral neuropathy

In this Review, we discuss the progress made in the development of such modulators for the treatment of depression, and examine recent preclinical and translational studies that have investigated the mechanisms of action of glutamate-targeting antidepressants

Therapies targeting lipid peroxidation in traumatic brain injury