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According to Kannt & Pfenninger in Frontiers in Physiology , NAD is a critical coenzyme in mitochondrial energy metabolism, and strategies that preserve NAD have wide-ranging effects on health and performance (Kannt & Pfenninger, Frontiers in Physiology )

Supplementation supports nervous system health and may alleviate symptoms of carpal tunnel syndrome and neuropathic pain source

Genetically predicted higher l-carnitine was associated with lower HDL-cholesterol in men (effect size 0.04, 95% CI 0.06 to 0.02), and not in women (0.004, 95% CI 0.05 to 0.06, p value=0.88)

Double-Blind Intervention Trial on Modulation of Ozone Effects on Pulmonary Function by Antioxidant Supplements

It also helps support healthy weight management and exercise performance