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For many experiment, we also used 10 nM of ligand for stimulation, which is a more physiological level than the 100 nM used in many previous experiments

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And, pretreatment with Moringa oleifera leaf extract (400 mg/kg/day for 14 days) produced anxiolytic effects in both FST and tail suspension test (TST) in the hepatic encephalopathy mouse model (139)

The exact mechanism of ferroptosis induction and its interaction with cancer cells is also not fully understood, and further studies are needed to elucidate how this pathway can be efficiently manipulated ( To translate these findings into clinical practice, further investigation is needed to elucidate the molecular mechanisms of ferroptosis, explore potential combinatory therapies, and develop robust biomarkers