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[60] reported that ALA regulated the translocation of HMGB1 through the HMGB1/TLR4/NF-B pathway, preventing apoptosis and oxidation, thus inhibiting myocardial IR injury (Figure 5D)

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Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit tumor necrosis factor alpha transcriptional activation by regulating nuclear factor-kB and cAMP response element-binding protein/c-Jun J Biol Chem 1998 273 : 3142731436 Russo SM, Tepper JE, Baldwin AS Jr, Liu R, Adams J, Elliott P, Cusack JC Jr

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S2 subunit-targeting antibodies isolated from convalescent patients showed weaker neutralizing activities against SARS-CoV-2 than RBD-targeting antibodies 64