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Nausea affects approximately 44% of participants in pooled STEP trial data, with diarrhea (30%), vomiting (24%), and constipation (24%) also common

AOD 9604 differs by acting on fat metabolism without elevating IGF-1 levels

Third-party tested

Therefore, the methylation of NA catalyzed by NNMT is inhibited, and the product, MNA, is reduced

Theoretical concerns about chronic NNMT inhibition include effects on the metabolism of other quinolinium and methylpyridinium endogenous metabolites and on the broader cellular methylation landscape