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Briefly, the cells were resuspended in LacZ buffer, permeabilized by the addition of 50 ml chloroform and 20 ml SDS (0.1%)

Life Sci 2022;291:120260

In fact, sirtuin pharmacological activation has been shown to promote protective effects in several cardiovascular diseases, such as hypertension, fibrosis, hypertrophy, and arrhythmias [138,139,140,141]