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An overexpression study has shown that T185S variation destabilizes TMEM106B protein [61], but this is not supported by other cell culture and mouse studies [135, 150, 152, 153]

Ignoring storage requirements Leaving reconstituted peptides at room temperature, exposing them to light, or using vials beyond their stability window degrades the compounds before they ever reach your tissue

Currently, several studies have indicated that early improvement in the hypoxic state of the infarct site can benefit ischemia stroke treatment [129, 130]