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urinaria , including quercetin 3-O--L-rhamnopyranoside, quercetin, quercetin 3-O--L-(2,4-di-O-acetyl)rhamnopyranoside-7-O--L-rhamnopyranoside, and quercetin 3-O--L-(3,4-di-O-acetyl)rhamnopyranoside-7-O--L-rhamnopyranoside ( Lignans metabolites in P

To comprehensively characterize this phenomenon, we conducted a PRISMA-ScR-guided exploratory review across four major databases (PubMed, Scopus, Web of Science, Dimensions), identifying 343 eligible records spanning 2010-2025

Its natural origin makes quercetin particularly appealing as a therapeutic option, especially for patients who are resistant to or experience adverse reactions to conventional treatments

These lesions are thought to contribute to neuronal dysfunction and ultimately neuron death, synaptic loss, and brain atrophy (shrinkage), particularly in brain regions involved in memory such as the hippocampus and cerebral cortex