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The genome editing methods are based on the manipulations of the nucleotide sequences in a strictly specified location and with a minimum number of off-target changes in the genome, and are supposed to be environmentally friendly

doi: 10.1159/000228994 7 LibertiMVLocasaleJW

Elevated estrogen can further increase histamine by stimulating mast cells to release histamine and decreasing diamine oxidase (DAO), the enzyme responsible for breaking down ingested histamine

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