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A Novel Antagonist of the Prostaglandin E(2) EP(4) Receptor Inhibits Th1 Differentiation and Th17 Expansion and Is Orally Active in Arthritis Models

pylori , CagA and the type 4 secretion system (T4SS), are encoded by the cytotoxin-associated gene pathogenicity island (cagPAI) and play a crucial role in carcinogenesis [43]