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These findings explain our earlier observation that the W234R mutant has a markedly improved catalytic activity with most substrates tested to date compared to the wild-type enzyme

Mourad, F.A

[122] demonstrated that patients with COPD and overweight smokers have impaired endothelial function [122]

Glutathione injections involve the direct administration of glutathione, a naturally occurring antioxidant found in the body, through intramuscular or intravenous methods

Immune cells, such as macrophages and neutrophils, can also generate ROS due to their oxygen-dependent mechanisms to fight against invading microorganisms based on NOX2 isoform (Finkel, 2011)