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6.3.3 Core challenges and future directions Several critical challenges remain to be addressed for the clinical translation of SSP-targeted therapy

In this group, there were 47 children with an additional diagnosis of Lyme disease as determined by reputable authorities in infectious disease and this analysis has been addressed in Part 2 in the series

Kynurenine is involved in the biosynthesis of neuroprotective metabolites like kynurenic acid, which modulates glutamate activity and inflammation 33

[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Oliva M, Muoz-Aguirre M, Kim-Hellmuth S, Wucher V, Gewirtz ADH, Cotter DJ, et al