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Ethics declarations Ethics approval and consent to participate The study protocol was approved by the ethics committee of Guilan University of Medical Sciences (IR.GUMS.REC.1400.197) in accordance with the World Medical Associations code of ethics (Declaration of Helsinki, revised in Brazil 2013), and registered at an ICMJE and WHO recognized registry of clinical trials (www.irct.ir) at 28/08/2021 (registration number: IRCT20200920048782N1)

Lyophilised peptides must be reconstituted with bacteriostatic water at controlled temperatures

They've got a total of 6 ingredients in common

Alcohol disrupts neurotransmitter regulation, especially glutamate and GABA, and acamprosate helps normalize that balance once abstinence begins