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Biochem Pharmacol 213:115619

Cisplatin and paclitaxel co-delivered by folate-decorated lipid carriers for the treatment of head and neck cancer

(2009) also found that oxidation at His54 and His55 was associated with Mn-SOD deactivation in human medulloblastoma cells (John et al., 2009)

The fresh media were replaced every 2 days

Timing: Dosing is most often administered in the evening, shortly before bedtime, to align with its hypothesized promotion of SWS and natural circadian rhythms