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Finally, signals were visualized using an Odyssey CLx imaging system (LI-COR, USA)

A prolongated cholesterol load has been related to mitochondrial dysfunction and cellular apoptosis 61

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Endothelial cells, pericytes and local blood supply Blood supply to the ONH originates in the ophthalmic artery which branches into the central retinal artery, perfusing the nerve fiber layer (Figure 10) and two posterior ciliary arteries