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This imbalance can be caused by intense exercise, UV exposure, pollution, or poor diet

Moreover, ECM stiffness is sensitive to exogenous TGF- stimulation through inhibiting the interaction of inner nuclear membrane protein LEM domain-containing protein 3 (LEMD3) and SMAD2/3

These results suggest that Gpx1 deficiency attenuates Con A-induced liver injury

The fact that the drop in EI can be fitted to a sigmoid pattern suggests a typical average and spread of a biological population of individual cells dealing with the stress on them