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The hydrophobic pockets, thiol residue, and surface-exposed termini of albumin make it suitable for acting as a carrier for a range of peptidyl and non-peptidyl drugs

These findings were met with enthusiasm, as GlyT1 inhibition demonstrated promise in ameliorating specific symptoms and cognitive deficits in some neurodegenerative conditions (Bridges et al

Marking its place as the fourth ALS treatment and pioneering the way as the inaugural gene therapy to gain accelerated approval anchored in biomarker evidence, tofersen is a landmark in the field of gene therapy for ALS (45)

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Besselink-Lobanova A, Maandag NJ, Voermans NC, van der Heijden HF, van der Hoeven JG, Heunks LM