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The New England Journal of Medicine, 389(16), 1463-1476

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Because an oral 15-PGDH inhibitor has already passed Phase 1 safety testing in humans for age-related #muscle weakness, the authors are hopeful that clinical trials in joint disease will follow, potentially paving the way for #nonsurgical, cartilage-regenerating therapies that could delay or replace knee and hip replacements

524 Folate is crucial to normal neurodevelopment

This matters because your body naturally makes less collagen as you age and the collagen you have left breaks down faster, so supporting that process directly is more useful than masking the surface