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One study that came out after I published the book that was so inspiring with the men they took two groups of men and had the first group eat mostly packaged, highly processed foods for three weeks

10.1371/journal.pone.0075812 40 ElustondoP

They do get destroyed en masse whenever they show up, but they are ultimately just weapons and defeating them is usually a Pyrrhic Victory with the exception of the Final Fantasy XIV crossover event where their manifestation as the False Idol / Her Inflorescence is safely defeated and banished from that world, though even then it's hinted that there is still an active Seed of Resurrection in there

10.1016/j.neuropharm.2020.108380 Neuropharmacology 261 WestA

To determine LD50, groups of test animals, such as rats, are exposed to an ever-increasing amount of a toxic substance, or a dose