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Supplementary file1 (MP4 16521 kb) Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made

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Although the potential gene-environment interactions that have been identified are of small to moderate magnitude (probably limited by the number of populations included), 80,81 we should regard hereditary variants and environmental factors as additive risks in the prediction of breast cancer susceptibility

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