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MPO is an enzyme that carries out peroxidative activities and is released by neutrophils, also reflecting the state of neutrophils in the innate immune response (73)

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Ex vivo analysis of mitochondria derived from rats subjected to ballistic injury revealed decreases in the enzymatic activity of pyruvate dehydrogenase and glutamate dehydrogenase, which reduce input from glucose and glucogenic AAs into the citric acid cycle (reduced CoA-SH and acetyl-CoA concentrations), at 24 h after injury [72, 75]