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Cell (2018) 174(6):155970.e22

TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells

In a series of 138 cases of methemoglobinemia, dapsone accounted for 42 percent, with a mean methemoglobin level of 7.6 percent (range 2 to 34 percent)

17% with placebo, though fibrosis stage did not significantly improve

Research indicates effects on reproductive hormones including normalization of disrupted LH pulsatility, suggesting potential applications in sleep-related reproductive dysfunction research