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S8D), H82 and H526 exhibited the highest NRF2 protein levels upon KEAP1 inhibition along with marked upregulation of the NRF2 target genes NQO1 and AKR1C3 , indicating that the NRF2 regulon is functional in those two cell lines (Fig

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These findings highlight that IFN- mediated and IFN-+NAC induced ER stress is dependent on presence of IFN-

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