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Since IRI generates oxidative stress, which is involved in various diseases, it is plausible that a reduction in oxidative stress could block kidney disease progression

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Increased PKC activity and altered GSK3/NMDAR function drive behavior cycling in HINT1-deficient mice: bipolarity or opposing forces

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations GSH: reduced glutathione GSSG: glutathione disulfide GS: thyil radical ROS: reactive oxygen species RNS: reactive nitrogen species RS: reactive species -GCS: -glutamylcysteine synthetase GPX: glutathione peroxidase GR: glutathione reductase GST: glutathione S -transferase GSNO: nitrosoglutathione G6PD: glucose-6-phosphate dehydrogenase NAC: N -acetyl-L-cysteine NO: nitric oxide protein-SSG: protein glutathionylation protein-SNO: protein nitrosylation References Galluzzi L, Maiuri MC, Vitale I, Zischka H, Castedo M, Zitvogel L et al

Bone turnover markers: In the elderly control group, OC decreased by 45% and CTX increased by 75%