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The peptide promotes osteoblast attachment, increases collagen synthesis in bone cells, and has demonstrated enhanced outcomes in ACL reconstruction studies in rats when administered via articular injection at 0.3 mg/mL

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It may also lead to the erroneous conclusion that IGF-I bioactivity is decreased

For this, triple immunofluorescence staining for DCX/BrdU/anti-4-hydroxynonenal (4HNE) and Tuj1/BrdU/4HNE was performed