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[PMC free article: PMC2995809] [PubMed: 20431058] 180

On the basis of data on irritancy in humans, a tolerable concentration can be derived as follows: 45 mg/m 3 Tolerable concentration = = 2 mg/m 3 (2000 g/m 3 ) 20 where: no effects were observed in a limited study on human volunteers at 45 mg/m 3 (Silverman et al., 1946) and 20 is the uncertainty factor (10 for intraspecies variation and 2 for the poor quality of the data)

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