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discussion 1146-1139

2021 Dec 26

14 The ROS and RNS can cause oxidative damage to DNA, lipids, carbohydrates and proteins, and thereby mediate an array of downstream processes that contribute to the development and progression of COPD

In fact, research has shown that oocytes with higher levels of intracellular glutathione produce healthier and stronger embryos (Mukherjee et al., 2014)

Additionally, oxidative stress impairs the cells ability to repair damaged DNA by affecting related signaling pathways and enzymes, promoting tumor cell proliferation and causing cell cycle arrest, which impacts overall cell proliferation