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[DOI] [PubMed] [Google Scholar] 138.Mahat R.K., Singh N., Rathore V

It is worth being equally candid about diagnosis: routine blood and urine testing has a role, but provoked (challenge) urine testing is controversial and not standardized giving a chelator predictably raises urinary metals in almost anyone, there are no validated reference ranges for the provoked result, and results must be interpreted with real caution rather than used to justify aggressive treatment

ROS can attack proteins to form carbonyls and react with nitrogen species and tyrosine to form nitrotyrosine