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The first objective landmark I rely on is the peak reticulocyte count 1 week after starting treatment

While NADPH sourced from glycolysis and the pentose phosphate pathway are commonly identified as the main contributors to redox balance, a significant amount of NADPH is also produced by the folate cycle, which is primarily driven by serine-derived one-carbon units 19

Blood-based biomarkers were selected using a descriptive PubMed search to assess how frequently individual biomarkers have been investigated in the context of IS biomarker research