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First, extracellular HSP27 directly competes with oxidized LDL for binding to scavenger receptor-A, blocking macrophage uptake of the oxidized cholesterol that initiates foam cell formation, an early step in plaque formation (Rayner 2008)

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The US Food and Drug Administration (FDA) has issued a warning letter to a medical spa company in Texas for violating the Drug Supply Chain Security Act (DSCSA) after finding the firm dispensed significantly more units of AbbVies Botox (onabotulinumtoxinA) than it purchased through legitimate channels