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1, 2020 NLS Tang, J Hui Department of Chemical Pathology, and Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China NLS Tang () MBChB, MD, FRCPA Metabolic Medicine, Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, 1 Shing Cheong Road, Kowloon Bay, Kowloon, Hong Kong SAR, China J Hui () MBBS, FRCP(Edin), FHKCPaed Correspondence to: Prof

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After this first round of reactions, the two carbon shortened Acyl-CoA is recycled through subsequent rounds of -oxidation reactions generating Acetyl-CoA that enters the TCA cycle allowing the ATP synthesis by the oxidative phosphorylation (Figure 1)