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mansoni pathology, experiencing profound metabolic disruptions due to chronic inflammation, fibrosis, and oxidative stress

BACH1 itself is a direct transcriptional target of HIF1A, which binds its promoter under hypoxic conditions to induce expression 174 , highlighting a multilayered transcriptional network linking hypoxia, GSH metabolism, and cuproptotic vulnerability

To further confirm an NRF2-dependent effect of DMF, we compared the expression of those ferroptosis-related factors including CBS in sh NRF2 cells

The exposed workers excreted an average of 9.7 (standard deviation [SD] = 11.6) mg of albumin per g of creatinine, significantly different from the nonexposed group value of 5.5 (SD = 4.3)

Statistical analysis The data analysis was performed using the IBM SPSS Statistics version 23.0 and values were expressed as the mean SEM