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Their advantage lies in the ability to sensitively capture the early cascade of events, ranging from impaired mitochondrial fatty acid oxidation to transport defects and tubular metabolic imbalance, thereby complementing the molecular trajectory of DKD that is not adequately reflected by conventional UACR measurements (Table 1)

It acts rapidly in the body, making it particularly suitable for periods of chronic fatigue, prolonged stress or exposure to environmental pollutants

This is also true of dysarthria, another type of motor speech disorder

Iron can directly promote -syn aggregation through structural links, leading to conformational changes (135)

a PEG-based polymeric chain is a linear poly(ethylene glycol) chain, of which one end is connected to the branching core and the other to a hyperbranched dendritic moiety