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Friedrichsen M, Breitschaft A, Tadayon S, Wizert A, Skovgaard D

doi: 10.3389/fmed.2023.1204198 65

To calculate the sensitivity (true positive rate) and specificity (true negative rate) of each in vitro liver test system for detection of carcinogenic (Table 3) or in vitro/in vivo mutagenic NAs, existing rodent cancer data or in vitro and in vivo mutagenicity data were used as supposed truth (see Table 1 and 4)