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doi: 10.1038/s44259-025-00102-6, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Zeng Q., Zhang Z., Chen P., Long N., Lu L., Sang H., et al

Cancers (Basel) 15 , 3868 (2023)

It should be noted that functional similarity between proteins is not always directly reflected by overall amino acid sequence similarity

Notably, age-related changes in DNA methylation patterns can be quantified through epigenetic (biological) clocks, offering measurable insights into biological age, distinct from chronological age (Fig