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Despite advancements like hybrid closed-loop systems and artificial pancreas technology, achieving optimal glycaemic control remains a challenge

Moreover, it is a form of bacteria with a fermentative metabolism that predominantly generates lactic acid without generating any toxic gases or catalase 6

PloS One (2012) 7(2):e32094

The first step involves ligation of -glutamate to cysteine to form -glutamylcysteine, a reaction catalyzed by GCL

Typically, the concentration of carnitine in plasma is in the low M range (~4060), while tissue concentrations (taken here to approximate cytoplasmic concentrations) are in the low mM range (~15 mM) 26,27