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Some protocols begin with a brief intensive phase (for example, daily or alternate-day dosing) followed by a maintenance phase (for example, weekly to monthly), particularly for B12 deficiency

Refrigerate immediately: Store the reconstituted vial in a closed box in the refrigerator

J Hepatol 20:138142

Common symptoms may include: Persistent tiredness or fatigue Weakness Shortness of breath Pale skin Pins and needles Difficulty concentrating Memory problems Low mood If symptoms are severe, prolonged or worsening, it is important to seek professional medical advice

The combination between DPI and vincristine was also synergistic but less potent