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In the past, many cultures have used the bark, needles, resin, and nuts of pine trees as medicine ( In the 1940s, scientist Jacques Masquelier began studying the health effects of pine bark after learning that indigenous peoples of North America were using pine bark tea to heal scurvy and wounds ( Since then, pine bark extract has continued to increase in popularity as an herbal supplement

doi:10.1016/j.chroma.2016.02.035 Krishnaiah C, Vishnu M, Kumar R, Mukkanti K (2011) Development of a stability-indicating UPLC method for determining olanzapine and its associated degradation products present in active pharmaceutical ingredients and pharmaceutical dosage forms

Additionally, milder forms of the condition may remain undetected [12]