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Preparation of knockout and stably expressing cell lines The CIP4 gene in PANC-1 cells was knocked out by using the CRISPR-Cas9 system

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GHK-Cu jest obecny w organizmie w niewielkich ilociach, a jego stenie zmniejsza si wraz z wiekiem, co sugeruje, e ma znaczenie w procesach zwizanych ze starzeniem si organizmu

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It was noted that TRF-administered rodents showed considerable improvement in their oxidant-antioxidant status comprising reductions in nitrogen oxide and malondialdehyde levels, as well as significantly elevated glutathione and increased activity of SOD and CAT