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Ubiquitination leads to covalent attachment of Ub, typically to lysine residues on target proteins, which eventually leads to monoubiquitination or polyubiquitination 120

As the key enzyme of the pentose phosphate pathway, G6PDH generates NADPH, which is essential for fatty-acid and steroid biosynthesis (Zhou et al., 2020)

Damaging coding variants within kainate receptor channel genes are enriched in individuals with schizophrenia, autism and intellectual disabilities

Glutathione is often referred to as the bodys master antioxidant because of its important role in supporting normal immune function, cellular metabolism, and overall cellular regulation

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis