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Where a hormone is often a single broad message, peptides tend to act as precise instructions, telling specific tissues to repair, specific cells to release growth hormone, or specific pathways to ramp up or quiet down

The contribution of gut bacterial metabolites in the human immune signaling pathway of noncommunicable diseases

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This mechanism results in a chronic upregulation of pro-inflammatory cytokines (i.e., TNF- and IL-6), which are known to exert deleterious effects on the insulin signaling pathway in adipocytes, hepatocytes, and myocytes (80)