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The role of pyroptosis in cancer: pro-cancer or pro-host

Ozone decreases the production of pro-inflammatory cytokinesparticularly IL-6, IL-1, and TNF-which are primarily responsible for cartilage degradation

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Investigated pathways include BPC-157-associated angiogenic and growth-factor signaling alongside TB-500-associated cell-migration, cytoskeletal, and inflammatory-response mechanisms