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Collagen fibers in the G/D-CuP group exhibited increased density, thickness, and organization compared to the G/M-CuP group, suggesting enhanced collagen deposition (Fig

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n = 20 nuclei were analyzed in each condition ( c,f,i )

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In this work, we identify NKX21 as a transcription factor driving the overexpression of serine/glycine synthesis enzymes and causing cell addiction to this pathway in cancer