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Nature 576:5160

elevated B12 may lower B6, disrupting keratin synthesis

These markers bear strong correlations with adverse conditions such as cardiovascular and metabolic diseases (eg, insulin resistance), underscoring the value of moderate physical activity

Acknowledgments We express our appreciation for the guidance received from the late Roberto Milanino, MD, of the University of Verona, who brought insight into the biological relevance of our research and to whose memory we dedicate this manuscript