PMID: 17110467 | DOI: 10.1096/fj.06-6328com [22] Hermsdorff HH, Zulet M, Abete I, Martnez JA
Continuum 28, 13011313
4151-A UNMET SYSTEMIC THERAPY NEED FOR CHILD-PUGH CLASS B PATIENTS WITH UNRESECTABLE HEPATOCELLULAR CARCINOMA COMPARISON OF ATEZOLIZUMAB PLUS BEVACIZUMAB AND LENVATINIB Hideko Ohama 1,2,3 , Atsushi Hiraoka 1,2 , Toshifumi Tada 2 , Masashi Hirooka 2 , Kazuya Kariyama 2 , Ei Itobayashi 2 , Tsuji Kunihiko 2 , Toru Ishikawa 2 , Hidenori Toyoda 2 , Takeshi Hatanaka 2 , Satoru Kakizaki 2 , Atsushi Naganuma 2 , Tomomitsu Matono 2 , Fujimasa Tada 1,2 , Kazuhiro Nouso 2 , Yoichi Hiasa 2 and Takashi Kumada 2 , (1)Ehime Prefectural Central Hospital, (2)Relpec Study Group and HCC 48 Group, (3)Takarazuka City Hospital Background: Systemic treatment is generally recommended for unresectable hepatocellular carcinoma (uHCC) patients with Child-Pugh (CP)-A status
NAFLD is becoming a major cause of liver-related morbidity worldwide, impacting nearly 25% of the global population, 10,11 and is typically associated with obesity, insulin resistance, diabetes, and dyslipidemia
Today, with the rapid development of computational technology, MD simulation can not only study single proteins but also analyze complex protein-protein/DNA/RNA complexes (Norberg and Nilsson, 2003