Rather than observing increasing and persistent JNK activation (persistent pJNK), rising ROS levels, peroxynitrite formation, and release of Endo G and AIF, instead they found pJNK decreased over time to undetectable levels, and hepatic necrosis was prevented ( Figure 22 )
Meier (19472021)
Globally, approximately 1% of people over the age of 60 suffer from PD, but in 10% of cases, the disease occurs at a younger age and is referred to as early-onset PD (Mchtel et al
10.2741/4286 103 ZuhraK.AugsburgerF.MajtanT.SzaboC
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