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During drug screening experiments for amlexanox, a drug used in the treatment of asthma and aphthous ulcers, it was discovered that amlexanox inhibits both IKK and TBK12 kinases and reduces body weight in diet-induced or genetically obese animals by increasing energy expenditure

At high levels, CAT converts two molecules of hydrogen peroxide in a single reaction due to its catalytic activity

Particularly, the cross-talk between the endothelial cells and components of the NVU preserves the BBB integrity

Analgesic peptides in Buthus martensii Karsch: a traditional Chinese animal medicine the analgesic peptides in scorpion venoms

PubMed Central, Tavares, M., et al