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There is little high-quality long-term safety surveillance of the sort that would usually be expected before confidently promoting a peptide for preventive use in generally healthy people

Self-administration of injectable peptides by nave and inexperienced users carries serious health risks, ranging from injection-related injuries and infections to the transmission of serious diseases like Hepatitis C if needles are reused or shared

It remains possible that as NAD+ use becomes more widespread, some interactions could emerge

At a dose of 100 mg/kg, metformin caused a clear reduction in NF-B levels, which is quite similar to the control group

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