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Reduction in Spontaneous Tumor Incidence: Studies : Research, particularly in female Swiss-derived SHR mice, has indicated a decrease in the incidence of spontaneous tumors

Precautions During Treatment Folic Acid Masking: Taking large amounts of folic acid (Vitamin B9) supplements can mask or hide a B12 deficiency in blood tests while allowing the invisible nerve damage to silently worsen

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Due to the mediating position of the folate cycle between the two adjacent cycles, a folic acid deficiency has widespread consequences: the production of SAM falls, as does that of BH4 and the associated neurotransmitters